2019-03-25 London ,UK

Complications are set up with the struggle and severe effects, affecting parts of the body due to Diabetes. Controlled blood sugar will have less Diabetic complications, If the blood sugar level is not properly maintained then there would be more diabetic complications. The effects of Diabetes which include smoking, high diabetes, high cholesterol levels, obesity, high blood pressure, and lack of exercise.

• Macrovascular complications
• Microvascular complications
• Diabetic Foot Disease
• Diabetic Neuropathy
• Cerebrovascular
• Nonketotic Hyperosmolar Coma
• Stiff-person syndrome
• Auditory Impairment
• Diabetic ketoacidosis
• Diabetic cardiomyopathy
• Diabetic Retinopathy
• Toxaemia of pregnancy

The Trends in Diabetic complications are regarding the ideas and prediction of Diabetes Mellitus Type 1 and Diabetes Mellitus Type 2 with the market analysis of the Diabetic products and the outline structure of the Diagnostic Therapies environment in them. The Type 1 Diabetes is less trend factor and not huge complications for research fields. The Type 2 Diabetes is more trend and risk factors lead to abnormalities. According to the global increase in type 2 diabetes, the International trends in complications of type 2 is less clear.

• Hypertension
• Diabetic Gastroparesis
• Immune intervention in type 1 Diabetes
• Diabetic Myelopathy
• Latent Autoimmune Diabetes of Adults (LADA)
• Diabetic Mastopathy
• Euglycemia Gestational Diabetes
• Gender differences in hypoglycemia responses or metabolism
• Recent Trends in Diabetic Neuropathy
• Management of Diabetic Complications in recent ideas

In chronic diabetes the crash of blood glucose and insulin level leads to damage of body organs and systems. Endothelial cells take more glucose than normal, they don’t depend on insulin. Then they form more surface than normal that leads basement to increase thicker and weaker. If the insulin content become more that lead the chronic complications high. Chronic complications are of two types: Microvascular and Macrovascular.

Microvascular Complications:

·         Retinopathy

·         Neuropathy

·         Nephropathy

·         Diabetic foot

·         Dermopathy

Macrovascular Complications:

·         Cerebrovascular

·         Cardiovascular

·         Lower Extremity Gangrene

·         Stroke

·         Myocardial Infraction

The Advanced technologies & treatments for diabetes are many according to the region and the specialty of the equipment availability. Every year creative minds and companies introduce a crop of high tech devices and treatments.

   Advanced Technologies for Diabetes:

• Blood Glucose Monitors
• Flash Glucose Monitoring
• Insulin Pumps
• Continuous Glucose Monitoring
• Bionic Pancreas
• Novo Pen Echo
• Smart Sox
• Glucose Buddy

    Treatments for Diabetes:

• Rapid activity insulin
• Pharmacotherapy
• Short activity insulin
• Sulfonylureas
• Meglitinides
• Biguanides
• Insulin mixtures
• Ultra-long acting insulin

Metabolic syndrome is a group of risk factors that develops the chance of developing cardiovascular diseases, stroke, and type 2 diabetes. It is also called as insulin resistance syndrome. Many disorders with metabolic syndrome doesn’t show any symptoms. Causes and risk factors of metabolic syndrome are age, obesity, inactivity, cardiovascular disease, diabetes, nonalcoholic fatty liver disease or polycystic ovary syndrome.

Now a day the young ones are suffering from diabetes which is passed from the genetics of their parents. Genetic Diabetes is caused by Monogenic and polygenic diseases. Monogenic disorder is caused by the mutation of single gene, which is also known as mendelian disorder. Polygenic disorder is caused by multiple genetic variants with low penetrance. The unresolved problem of polygenic disease or various identification methods are the raising factors of diabetes.

A Diabetic Coma is known as a life-threatening Diabetes complication that cause unconsciousness. It refers to the diagnostical dilemma posed when a physician is confronted with an unconscious patient about whom nothing is known except that they have diabetes.

     Types:

• Severe hypoglycemia
• Advanced diabetic ketoacidosis
• Nonketotic hyperosmolar coma

Diabetic Nursing means the nurse that helps the patients having diabetes, a disease that prevents the body from producing or absorbing enough insulin. A diabetes nurse’s greatest asset is their ability to communicate. Many of the diabetes nurses becomes advocates for diabetes awareness and go on to become diabetes educators. Diabetics specialist nurses provide training and support to non-specialist health care professionals including nurses in primary, secondary and community settings and care homes.

The current challenges in new therapies to diabetes complications is concerned with the current challenging problems of Diabetes Dyslipidemia, Diabetes, Parkinson and problems facing in development of new drugs for type 2 diabetes.   The scientist and researchers put their interest in solving the new problems of diabetes. The recent surgeries advantages and Bioinformatics tools and techniques used in Diabetes Research are discussed under the challenges of the diabetes complications.

The oxidative stress plays a key role in diabetic complications because the oxidative stress leads to the whole-body damage, vitamin deficiency and sleepiness. If the flow of blood glucose level is not on normal, then the body imbalance also takes place. Reactive Oxygen Species (ROS) deplete antioxidant defenses, rendering the affected cells and tissues more susceptible to oxidative damage. Lipid, DNA, and protein are the cellular targets for oxidation, leads to changes in cellular structure and function.

Antibiotics are known as the drugs that are used for the treatment of the bacterial infections. The patients with mild infections can be treated in outpatient settings with oral antibiotics that cover skin flora including Streptococci and Staphylococcus. Diabetic patients have impaired ability to resist infection. There are many appropriate antibiotic regimes for almost any situation. Many antibiotics are advertised to have activity against clinically important bacteria. 

Herbal Medicine for Diabetes is extracting the medicine from the natural sides and the herbal sides. Ancient tradition people uses the herbal medicine for all the types of diseases, which is made from plant’s roots, leaves, berries, bark, flowers. Many people believe "natural medicine" are always good and safe for them so use herbal medicines to maintain or improve their health. The use of herbal remedies is more prevalent in patients with chronic diseases asthma, end-stage renal disease, all Endocrine Disorders such as diabetes, Osteoporosis, Pancreas Disorders and Adrenal Disorders etc.

Epidemiology concerns with identifying health-related causes and effects. Analytical Epidemiology aims to research, study risk, protecting factors of diseases, identify factors in a diseased population that varies from a non-diseased population. Descriptive epidemiology helps to describe disease within a population, it helps to understand the occurrence of disease. The usual way to gain this knowledge is by group comparisons. Analytical epidemiology determines the cause of an outbreak. Using the case control method, the epidemiologist can look on the major factors that may causes the disease. The epidemiology and public health relating the associated terms of diabetes with the epidemiology.

Market analysis for Diabetic products are mainly by the Manufacturer and the Marketing side. According to market analysis report key players include Novo Nordisk, Eli Lilly, Roche, Medtronic etc. Novo Nordisk is a leading global provider of diabetes products. Eli Lilly is the largest producer of insulin. Market analysis for Diabetic products discuss the easier way of treating the diabetes by the public opinion. Glucose monitoring has major marketing.